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<p>After-hours trading was used primarily by institutional investors until mid-1999, when ECN services became more widely available to retail investors. An ECN not only allows individual investors to interact electronically but also lets large institutional investors interact anonymously, thereby hiding their actions. <br></p>
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<p id="isPasted">If you have an open trade running and the market closes for the weekend, whatever loss or profit you have will freeze until the market opens again and sometimes there will be a gap that might shoot you into further loss or profits as the market resumes its movement. So technically yes, you can.</p>